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What are platelet-rich fibrin (PRF) injections?

Platelet-rich fibrin (PRF) is the second generation of platelet-rich plasma (PRP), and the injections are used to rejuvenate skin. PRF injections are made from your own blood and a protein matrix called fibrin. Once harvested, it becomes a gel made up of a high concentration of white blood cells, fibrin, and stem cells (growth factors).


How do PRF injections work?

Platelet-rich fibrin injections help stimulate healing. This specific platelet mixture helps build tissue, as fibrin is known to stimulate stem cells which improve collagen and elastin in the skin. PRF can help make the skin heal at the cellular level as fibrin responds positively to an injury.


Who can benefit from PRF injections?

PRF injections are safe for anyone who wants more youthful-looking skin in areas of the face and neck. PRF injections are also used to stimulate hair growth; therefore they may be a valid treatment for those suffering from hair loss. They are also used to help wounds with healing, which is why PRF injections are being used in the dental industry as well.

Depending on their concerns, most people are appropriate candidates for PRF therapy. One of the key benefits of PRF is that it is a minimally invasive procedure with a low chance of complications.

It offers excellent clinical outcomes as well, such as reducing the chance of complications or implant failure, which is especially beneficial in older patients with age-related illnesses.


What does a PRF treatment entail?

First, you will meet with an experienced provider to examine your skin concerns and determine whether platelet-rich fibrin treatment is right for you. PRF is derived from your blood. One vial of blood is obtained from your arm prior to the therapy precisely like we would for a regular blood test. Following that, the blood is deposited in a centrifuge to separate the PRF from other blood components. The PRF is extracted from the top of the vial and inserted into a syringe once the separation is complete. After that, it’s injected into your skin.

PRF treatments are done over a six to eight-week period. Longer-term effects will take treatments over three to four months that typically last six to twelve months. PRF treatments entail harvesting of your own blood which becomes a gel after 15-20 minutes when it is then re-injected into the problem area.


What areas of the face respond best to PRF injections?

PRF treatments are commonly used to help fill creases around and under the eyes, around the mouth, and the temples.


How much do PRF injections cost?

Cost is based on the number of PRF injections used to achieve your final treatment goal. Since the total number of injections and the total number of treatment sessions vary between patients, so does cost. During your consultation at our office, we will examine you and give you an estimate.


Is PRF filler safe?

While the FDA doesn’t approve platelet-rich treatments, they have support in the medical dermatology community. Many doctors have seen great success with the healing properties of PRF and PRP injections.

Because the platelet-rich fibrin treatment is a byproduct of the patient’s blood, disease transmission is not a concern, and the treatment is quite safe.


Contact our office

Contact our office today and book a consultation with one of our trained professionals to learn more about platelet-rich fibrin in Bend, OR. Our goal at Deschutes Dermatology Center is to help individuals improve their health and quality of life by combating the signs and symptoms of aging.




Please schedule a full consultation with our office to decide which service is the best option for you. During the appointment, you and your provider will discuss medical history, benefits and expectations.